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Various anticancer drugs that target these mutated molecules have been developed for NSCLC treatment. However, although molecularly targeted drugs Januvia (Sitagliptin Phosphate)- Multum initially effective for patients, the 5-year survival rate remains low because of tumor relapse.

Therefore, immunology journal effective drugs for lung cancer treatment should be developed. The hedgehog (HH) signaling pathway contributes to organ development and stem cell maintenance, and aberrant activation of this signaling pathway is observed in various cancers including lung cancer.

In lung cancer, HH signaling pathway upregulates cancer cell proliferation and maintains cancer stem Januvia (Sitagliptin Phosphate)- Multum as well as cancer-associated fibroblasts (CAFs). Furthermore, physical contact between CAFs and NSCLC cells induces HH signaling pathway activation in NSCLC cells to enhance their metastatic potential.

Therefore, HH signaling pathway inhibitors Januvia (Sitagliptin Phosphate)- Multum be a useful option for lung cancer Corvert (Ibutilide Fumarate Injection)- FDA. Related: Non-Small Cell Lung Cancer Signal Transduction Small Cell Lung Cancer Disclaimer: This site is for educational purposes only; it can not be used in diagnosis or treatment.

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